APOA1 Protein (AA 25-267) (His tag)

Catalog No. ABIN667126

Recombinant APOA1 protein expressed in Escherichia coli (E. coli).

Quick Overview for APOA1 Protein (AA 25-267) (His tag) (ABIN667126)

Target: APOA1 (Apolipoprotein A-I (APOA1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 25-267

Purification tag / Conjugate: This APOA1 protein is labelled with His tag.

Characteristics: Apolipoprotein A-1, 25-267 aa, Human, His-tagged, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing, 10% glycerol

Storage: 4 °C

Target Details

Target: APOA1 (Apolipoprotein A-I (APOA1))

Alternative Name: Apolipoprotein A-1

Background: Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It is the major protein component of high density lipoprotein (HDL) in plasma. This protein promotes cholesterol efflux from tissues to the liver for excretion. And it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the ApoA-1 gene are associated with HDL deficiency including Tangier disease. Recombinant human Apolipoprotein A-1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: APOA1, apolipoprotein A-I,. NCBI no.: NP_000030

Molecular Weight: 30.3 kDa (264aa), confirmed by MALDI-TOF.

Pathways: Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism