GRP78 Protein (AA 20-650) (His tag)
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- Target See all GRP78 (HSPA5) Proteins
- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-650
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Origin
- Human
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Source
- Hi-5 Cells
- Purification tag / Conjugate
- This GRP78 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- BIP, 20-650aa, Human, His tag, Hi-5 Cell
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HSPA5 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 200mM NaCl
- Storage
- 4 °C
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- Target
- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
- Alternative Name
- BIP (HSPA5 Products)
- Background
- Binding immunoglobulin protein (BiP) belongs to the family of ~70 kDa heat shock proteins (HSP 70). It is a stress response protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. This protein is essential for the proper glycosylation, folding as well as for the maintenance of cell homeostasis and the prevention of apoptosis. Recombinant human BIP protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography. Synonyms: Binding immunoglobulin protein, HSPA5, heat shock 70kDa protein 5, GRP78, glucose-regulated protein 78kD, MIF2. NCBI no.: NP_005338
- Molecular Weight
- 71kDa (640aa)
- Pathways
- Thyroid Hormone Synthesis, ER-Nucleus Signaling
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