VTA1 Protein (AA 1-307) (His tag)

Catalog No. ABIN667681

Recombinant VTA1 protein expressed in Escherichia coli (E. coli).

Quick Overview for VTA1 Protein (AA 1-307) (His tag) (ABIN667681)

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 1-307

Purification tag / Conjugate: This VTA1 protein is labelled with His tag.

Characteristics: VTA1, 1-307aa , Human, His tag, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl

Storage: 4 °C

Target Details

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Alternative Name: VTA1

Background: VTA1 (Vps20-associated 1 homolog), also known as LIP5 (LYST-interacting protein 5), DRG1 (Dopamine-responsive protein DRG-1), SBP1 (SKD1 bindingprotein 1), belongs to the VTA1 family. This protein Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Also, VTA1 is known to interact with CHMP1B, CHMP2A, CHMP5, VPS4B, KIAA0174 (IST1) and possibly CHMP3. Recombinant human VTA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: vacuolar protein sorting-associated protein VTA1 homolog, DRG-1, DRG1, LIP5, SBP1. NCBI no.: NP_057569

Molecular Weight: 36.5kDa (331aa), confirmed by MALDI-TOF