DIABLO Protein (AA 56-239) (T7 tag)
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- Target See all DIABLO Proteins
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 56-239
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DIABLO protein is labelled with T7 tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SMAC/Diablo, 56-239aa, Human, T7 tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DIABLO Protein
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Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 61-239) protein (His-IF2DI Tag)
DIABLO Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Second Mitochondria-Derived Activator of Caspase (DIABLO) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DIABLO Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Second Mitochondria-Derived Activator of Caspase (DIABLO) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)DIABLO Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid in 20mM Tris pH 7.5
- Storage
- 4 °C
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- Target
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- Alternative Name
- SMAC/Diablo (DIABLO Products)
- Background
- Smac/Diablo is one of the proapoptotic proteins. Smac promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding to inhibitor of apoptosis proteins (IAPs) and removing their inhibitory activity. Recombinant human Smac fused to T7-tag. at N-terminus was expressed in E.coli and purified by conventional chromatography techniques. Synonyms: SMAC3, DIABLO-S, FLJ10537, FLJ25049, Diablo isoform 1, SMAC/Diablo, Diablo isoform 1 0610041G12Rik, DBOH, Diablo homolog, DIABLO S, Diablo homolog (Drosophila), Mitochondrial Smac protein, Diablo homolog mitochondrial, SMAC 3, Smac protein, Direct IAP binding protein with low pI, Second mitochondria derived activator of caspase. NCBI no.: NP_063940
- Molecular Weight
- 22 kDa (199 aa), confirmed by MALDI-TOF.
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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