BAG3 Protein (AA 1-575) (His tag)
-
- Target See all BAG3 Proteins
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-575
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BAG3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
-
MSAATHSPMM QVASGNGDRD PLPPGWEIKI DPQTGWPFFV DHNSRTTTWN DPRVPSEGPK ETPSSANGPS REGSRLPPAR EGHPVYPQLR PGYIPIPVLH EGAENRQVHP FHVYPQPGMQ RFRTEAAAAA PQRSQSPLRG MPETTQPDKQ CGQVAAAAAA QPPASHGPER SQSPAASDCS SSSSSASLPS SGRSSLGSHQ LPRGYISIPV IHEQNVTRPA AQPSFHQAQK THYPAQQGEY QTHQPVYHKI QGDDWEPRPL RAASPFRSSV QGASSREGSP ARSSTPLHSP SPIRVHTVVD RPQQPMTHRE TAPVSQPENK PESKPGPVGP ELPPGHIPIQ VIRKEVDSKP VSQKPPPPSE KVEVKVPPAP VPCPPPSPGP SAVPSSPKSV ATEERAAPST APAEATPPKP GEAEAPPKHP GVLKVEAILE KVQGLEQAVD NFEGKKTDKK YLMIEEYLTK ELLALDSVDP EGRADVRQAR RDGVRKVQTI LEKLEQKAID VPGQVQVYEL QPSNLEADQP LQAIMEMGAV AADKGKKNAG NAEDPHTETQ QPEATAAATS NPSSMTDTPG NPAAP - Characteristics
- BAG3, 1-575aa, Human, His tag, E.coli
- Purity
- > 90% by SDS-PAGE
- Top Product
- Discover our top product BAG3 Protein
-
BCL2-Associated Athanogene 3 (BAG3) (AA 1-575) protein (GST tag)
BAG3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Associated Athanogene 3 (BAG3) (AA 2-577) protein (His tag)BAG3 Origin: Mouse Host: Yeast Recombinant > 90 % SDS
BCL2-Associated Athanogene 3 (BAG3) (AA 2-577) protein (His-SUMO Tag)BAG3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
BCL2-Associated Athanogene 3 (BAG3) protein (Myc-DYKDDDDK Tag)BAG3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM EDTA, 0.1mM PMSF, 10% glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
-
- Target
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- Alternative Name
- BAG3 (BAG3 Products)
- Background
- BAG3 was reported initially as a protein-refolding cochaperone of the bcl2 binding protein BAG family and as upregulated in response to persistent stress of cellular calcium balance dysregulation. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. Also, it has been shown to diminish stress-induced apoptosis. Recombinant human BAG3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 63.7 kDa (595aa)
- NCBI Accession
- NP_004272
-
