tau Protein (AA 1-352) (His tag)
-
- Target See all tau Proteins
- tau (tau Protein)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-352
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This tau protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Tau, 1-352aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product tau Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M Nacl, 1mM DTT, 10% glycerol
- Storage
- 4 °C
-
- Target
- tau (tau Protein)
- Alternative Name
- Tau (tau Products)
- Background
- MAPT, also known as TAU, is a neuronal microtubule associated protein found predominantly on axons. The function of this protein is to promote tubulin polymerisation and stabilise microtubules, but it also serves to link certain signalling pathways to the cytoskeleton. MAPT, in its hyperphosphorylated form, is the major component of paired helical filaments (PHF) and neurofibrillary lesions in Alzheimer's disease (AD) brain. Recombinant human MAPT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TAU, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, Microtubule-associated protein tau. NCBI no.: NP_058525
- Molecular Weight
- 38.9 kDa (372aa) confirmed by MALDI-TOF (Real molecular weight on SDS-PAGE will be shift up)
-