DUSP19 Protein (AA 65-217) (His tag)
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- Target See all DUSP19 Proteins
- DUSP19 (Dual Specificity Phosphatase 19 (DUSP19))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 65-217
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DUSP19 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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QVGVIKP WLLLGSQDAA HDLDTLKKNK VTHILNVAYG VENAFLSDFT YKSISILDLP ETNILSYFPE CFEFIEEAKR KDGVVLVHCN AGVSRAAAIV IGFLMNSEQT SFTSAFSLVK NARPSICPNS GFMEQLRTYQ EGKESNKCDR IQENSS - Characteristics
- DUSP19, 65-217aa, Human, His tag, E.coli
- Purity
- > 85% by SDS-PAGE
- Top Product
- Discover our top product DUSP19 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- DUSP19 (Dual Specificity Phosphatase 19 (DUSP19))
- Alternative Name
- DUSP17/DUSP19 (DUSP19 Products)
- Background
- Dual specificity phosphatase 19, also known as DuSP19, is a member of the dual specificity protein phosphatase subfamily. DuSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DuSP19 is a protein phosphatase which functions as a stress-activated protein kinase pathway-regulating phosphatase. DuSP19 contains a variation of the consensus DuSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP class of DuSPs. Recombinant human DuSP19 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 19.4 kDa (176aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_543152
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