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EIF2S1 Protein (His tag)

EIF2S1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >90% WB
Rockland
Catalog No. ABIN6699814
Supplier Product No.: 009-001-r86s
  • Target See all EIF2S1 Proteins
    EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
    Protein Type
    Recombinant
    Origin
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 4
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This EIF2S1 protein is labelled with His tag.
    Application
    Western Blotting (WB)
    Supplier Product No.
    009-001-r86s
    Supplier
    Rockland
    Purpose
    EIF2S1 recombinant protein-HIS Epitope
    Purification
    Recombinant full length human EIF2S1 was expressed in E. coli cells using an N-Terminal his epitope. The purity was determined to be >90% by densitometry.
    Purity
    >90%
    Top Product
    Discover our top product EIF2S1 Protein
  • Application Notes

    Western_Blot_Dilution: User Optimized

    Other: Kinase Assay-User Optimized

    Application_Note: EIF2S1 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~ 40 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 μg/μL
    Buffer
    EIF2S1 Protein is stored in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
    Alternative Name
    EIF2S1 (EIF2S1 Products)
    Background

    Synonyms: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha

    Background: EIF2S1, also known as eukaryotic translation initiation factor 2, subunit 1 alpha, is a 35 kDa protein in which The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation and promotes the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP (1). The Ser51 in the mature human EIF2-alpha protein acts as the sole site of phosphorylation that leads to repression of protein synthesis. EIF2-alpha also plays an essential role in erythropoiesis (2). EIF2S1 Protein is ideal for investigators involved in Signaling Reagents, Protein Substrates, Angiogenesis, Cellular Stress, Inflammation, Neurobiology, and Ser/Thr Kinases research.

    NCBI Accession
    NM_004094
    Pathways
    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
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