EIF2S1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2720057

Product Details

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This EIF2S1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human EIF2A / EIF2S1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Alternative Name: Eif2a,eif2s1 (EIF2S1 Products)

Synonyms: EIF-2 Protein, EIF-2A Protein, EIF-2alpha Protein, EIF2 Protein, EIF2A Protein, Eif2s1 Protein, eif2s1l Protein, fb36a08 Protein, wu:fb36a08 Protein, zgc:56510 Protein, 0910001O23Rik Protein, 2410026C18Rik Protein, 35kDa Protein, Eif2a Protein, eIF2alpha Protein, eif2a Protein, CG9946 Protein, Dmel\\CG9946 Protein, Eif2alpha Protein, IF2A_DROME Protein, M(1)14C Protein, M(1)19-153 Protein, M(1)8e3-10 Protein, deIF2alpha Protein, eIF-2 Protein, eIF-2 a Protein, eIF-2 alpha Protein, eIF2 alpha Protein, eIF2-alpha Protein, eIF2a Protein, eiF-2alpha Protein, elF2alpha Protein, l(1)14Cf Protein, l(1)19-153 Protein, eukaryotic translation initiation factor 2 subunit alpha Protein, eukaryotic translation initiation factor 2, subunit 1 alpha a Protein, eukaryotic translation initiation factor 2, subunit 1 alpha Protein, eukaryotic translation initiation factor 2 alpha subunit Protein, Eukaryotic translation initiation factor 2 subunit 1 Protein, eukaryotic translation initiation factor 2 subunit alpha L homeolog Protein, eukaryotic translation Initiation Factor 2alpha Protein, EIF2S1 Protein, eif2s1a Protein, Eif2s1 Protein, eif2s1 Protein, LOC693063 Protein, CNI00230 Protein, THAPSDRAFT_105 Protein, if2a Protein, eif2s1.L Protein, eIF-2alpha Protein

Background: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2 MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3 MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010].

Molecular Weight: 35.9 kDa

NCBI Accession: NP_004085

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C