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IL4 Receptor Protein (AA 26-232) (Fc Tag)

IL4R Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN6809937
  • Target See all IL4 Receptor (IL4R) Proteins
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 26-232
    Origin
    • 22
    • 11
    • 7
    • 5
    • 4
    • 1
    Human
    Source
    • 22
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This IL4 Receptor protein is labelled with Fc Tag.
    Sequence
    AA 26-232
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL4R Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
  • Target
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Alternative Name
    IL-4 R alpha (IL4R Products)
    Synonyms
    IL4R Protein, il-4ra Protein, zgc:113063 Protein, CD124 Protein, IL-4RA Protein, IL4RA Protein, Il4ra Protein, IL4 Protein, Il4r Protein, interleukin 4 receptor Protein, interleukin 4 receptor, tandem duplicate 1 Protein, interleukin 4 receptor, alpha Protein, IL4R Protein, il4r.1 Protein, Il4r Protein, Il4ra Protein
    Background
    IL-4 R alpha is also known as IL4R, CD124, IL-4RA.This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitis, asthma, or eczema. The binding of IL-4 or IL-13 to the IL-4 receptor on the surface of macrophages results in the alternative activation of those macrophages. Interleukin-4 receptor has been shown to interact with SHC1.
    Molecular Weight
    50.4 kDa
    NCBI Accession
    NP_000409
    Pathways
    JAK-STAT Signaling, Positive Regulation of Immune Effector Process
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