Claudin 6 Protein (CLDN6) (AA 1-4) (mFc Tag)
Quick Overview for Claudin 6 Protein (CLDN6) (AA 1-4) (mFc Tag) (ABIN6961123)
Target
See all Claudin 6 (CLDN6) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-4
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Purification tag / Conjugate
- This Claudin 6 protein is labelled with mFc Tag.
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Purpose
- Recombinant human CLDN6 Protein with C-terminal mouse Fc Tag
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Specificity
- CLDN6 (Met1-Ala4) (Gln57-Gln78) (Arg145-Arg158) mFc (Pro99-Lys330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP
CLDN6 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC. ELISA, Imm, SPR, Func Active
Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLPCLDN6 Origin: Cynomolgus Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, SPR, Func Active
Claudin 6 (CLDN6) (AA 1-220) protein (His tag)custom-made CLDN6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 6 (CLDN6) (AA 1-219) protein (His tag)custom-made CLDN6 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 6 (CLDN6) (AA 1-219) (Active) protein-VLPCLDN6 Origin: Mouse Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, SPR, Func Active
Claudin 6 (CLDN6) proteinCLDN6 Origin: Human Host: Mammalian Cells MNP Membrane Nanoparticle
Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP (Biotin)CLDN6 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, SPR, Func Active
Claudin 6 (CLDN6) proteinCLDN6 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Claudin 6 (CLDN6) (AA 138-160) protein (Fc Tag)CLDN6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 6 (CLDN6) (AA 138-160) protein (mFc Tag)CLDN6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- Claudin 6 (CLDN6)
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Alternative Name
- CLDN6
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Background
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
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Molecular Weight
- predicted molecular mass of 31.6 kDa after removal of the signal peptide.
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Gene ID
- 9074
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UniProt
- P56747
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Pathways
- Hepatitis C
Target
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