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CXCR4 Protein (AA 1-38) (Fc Tag)

CXCR4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN6964154
  • Target See all CXCR4 Proteins
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-38
    Origin
    • 12
    • 4
    • 2
    • 1
    Human
    Source
    • 9
    • 5
    • 3
    HEK-293 Cells
    Purification tag / Conjugate
    This CXCR4 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human CXCR4 with C-terminal human Fc tag
    Specificity
    CXCR4 (Met1-Lys38) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CXCR4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Alternative Name
    CXCR4 (CXCR4 Products)
    Background
    This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
    Molecular Weight
    predicted molecular mass of 30.5 kDa after removal of the signal peptide. The apparent molecular mass of CXCR4-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P61073
    Pathways
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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