CXCR4 Protein (AA 1-38) (Fc Tag)
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- Target See all CXCR4 Proteins
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-38
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CXCR4 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CXCR4 with C-terminal human Fc tag
- Specificity
- CXCR4 (Met1-Lys38) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CXCR4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Alternative Name
- CXCR4 (CXCR4 Products)
- Background
- This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 30.5 kDa after removal of the signal peptide. The apparent molecular mass of CXCR4-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P61073
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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