TGFB3 Protein (Fc Tag)
Quick Overview for TGFB3 Protein (Fc Tag) (ABIN6964329)
Target
See all TGFB3 ProteinsProtein Type
Origin
Source
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Purification tag / Conjugate
- This TGFB3 protein is labelled with Fc Tag.
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Sequence
- TGFB3 (Leu24-Arg300)+hFc (Glu99-Ala330)
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Characteristics
- Tagged Protein: C-Human Fc tag
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Purification
- affinity purification
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Transforming Growth Factor, beta 3 (TGFB3) (AA 301-412) protein
TGFB3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 3 (TGFB3) (AA 301-412) protein (AVI tag,Biotin)TGFB3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 3 (TGFB3) (Active) proteinTGFB3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Transforming Growth Factor, beta 3 (TGFB3) (AA 24-412) protein (His tag)TGFB3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Transforming Growth Factor, beta 3 (TGFB3) (AA 1-412) protein (GST tag)TGFB3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with deionized water
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Preservative
- Without preservative
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Storage
- -80 °C
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Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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Expiry Date
- 12 months
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- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
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Alternative Name
- TGFB3
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Background
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Synonymes: ARVD, ARVD1, LDS5, RNHF, TGF-beta3
Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016] -
Molecular Weight
- 56 kDa
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UniProt
- P10600
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Pathways
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
Target
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