CD1d Protein (Fc Tag)
Quick Overview for CD1d Protein (Fc Tag) (ABIN6964383)
Target
See all CD1d (CD1D) ProteinsProtein Type
Origin
Source
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Purification tag / Conjugate
- This CD1d protein is labelled with Fc Tag.
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Sequence
- CD1D (Gln20-Ser301)+hFc(GLU99-ALA330)
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Characteristics
- Tagged Protein: C-Human Fc tag
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Purification
- affinity purification
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with deionized water
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Preservative
- Without preservative
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Storage
- -80 °C
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Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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Expiry Date
- 12 months
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- CD1d (CD1D) (CD1d Molecule (CD1D))
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Alternative Name
- CD1D
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Background
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Synonymes: CD1A, R3, R3G1
Description: This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] -
Molecular Weight
- 56.54 kDa
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UniProt
- P15813
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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