TNFRSF13C Protein (AA 7-76) (His tag)
Quick Overview for TNFRSF13C Protein (AA 7-76) (His tag) (ABIN7013191)
Target
See all TNFRSF13C ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 7-76
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Purification tag / Conjugate
- This TNFRSF13C protein is labelled with His tag.
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Characteristics
- Cynomolgus BAFFR / TNFRSF13C Protein, His Tag
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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Alternative Name
- BAFFR
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Background
- BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
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Molecular Weight
- 9.1 kDa
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NCBI Accession
- XP_005567184
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Pathways
- NF-kappaB Signaling
Target
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