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OV16 (AA 17-197) protein (GST tag)

Origin: Onchocerca volvulus Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7013612
  • Target
    OV16
    Protein Type
    Recombinant
    Protein Characteristics
    AA 17-197
    Origin
    Onchocerca volvulus
    Source
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    GST tag
    Characteristics
    Onchocerca volvulus OV16 protein, GST Tag
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    OV16
    Background
    The OV16 antigen, localizes to the hypodermis, cuticle, and uterus of female O. volvulus is regarded as a highly sensitive and specific antigen for detection of IgG4 in people with prior exposure to onchocerciasis. It has an open reading frame that encodes a 152- amino acid polypeptide containing a 16-amino acid putative signal peptide. Enzyme-linked Immunosorbent Assay serological testing of OV-16 antigen is a diagnostic tool for determining effective elimination of the parasite.
    Molecular Weight
    46.8 kDa
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