OV16 (AA 17-197) protein (GST tag)
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- Target
- OV16
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-197
- Origin
- Onchocerca volvulus
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- GST tag
- Characteristics
- Onchocerca volvulus OV16 protein, GST Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- OV16
- Background
- The OV16 antigen, localizes to the hypodermis, cuticle, and uterus of female O. volvulus is regarded as a highly sensitive and specific antigen for detection of IgG4 in people with prior exposure to onchocerciasis. It has an open reading frame that encodes a 152- amino acid polypeptide containing a 16-amino acid putative signal peptide. Enzyme-linked Immunosorbent Assay serological testing of OV-16 antigen is a diagnostic tool for determining effective elimination of the parasite.
- Molecular Weight
- 46.8 kDa
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