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OV16 (AA 17-197) protein (GST tag)

Recombinant protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7013612

Quick Overview for OV16 (AA 17-197) protein (GST tag) (ABIN7013612)

Target

OV16

Protein Type

Recombinant

Origin

Onchocerca volvulus

Source

  • 2
  • 1
Escherichia coli (E. coli)

Purity

>95 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 17-197

    Purification tag / Conjugate

    GST tag

    Characteristics

    Onchocerca volvulus OV16 protein, GST Tag

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C
  • Target

    OV16

    Background

    The OV16 antigen, localizes to the hypodermis, cuticle, and uterus of female O. volvulus is regarded as a highly sensitive and specific antigen for detection of IgG4 in people with prior exposure to onchocerciasis. It has an open reading frame that encodes a 152- amino acid polypeptide containing a 16-amino acid putative signal peptide. Enzyme-linked Immunosorbent Assay serological testing of OV-16 antigen is a diagnostic tool for determining effective elimination of the parasite.

    Molecular Weight

    46.8 kDa
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