DPP4 Protein (AA 29-766) (His tag)
Quick Overview for DPP4 Protein (AA 29-766) (His tag) (ABIN7092747)
Target
See all DPP4 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 29-766
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Purification tag / Conjugate
- This DPP4 protein is labelled with His tag.
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Purpose
- Recombinant Human CD26 with C-terminal 6xHis tag
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Specificity
- CD26 (Asn29-Pro766) 6xHis tag
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
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Alternative Name
- CD26
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Background
- The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020]
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Molecular Weight
- predicted molecular mass of 111.5 kDa after removal of the signal peptide.The apparent molecular mass of CD26-His is 100-130 kDa due to glycosylation.
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UniProt
- P27487
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Pathways
- Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
Target
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