CDH6 Protein (His tag)

Catalog No. ABIN7199019

This Recombinant CDH6 protein is produced in HEK-293 Cells.

Quick Overview for CDH6 Protein (His tag) (ABIN7199019)

Target: CDH6 (K-Cadherin (CDH6))

Protein Type: Recombinant

Origin: Cynomolgus, Rhesus Monkey

Source: HEK-293 Cells

Purity: >90 % as determined by SDS-PAGE.

Product Details

Purification tag / Conjugate: This CDH6 protein is labelled with His tag.

Purpose: Cynomolgus / Rhesus macaque Cadherin-6 / KCAD / CDH6 Protein, His Tag

Sequence: Thr 22 - Gly 614

Characteristics: Cynomolgus / Rhesus macaque Cadherin-6, His Tag (CA6-C52H3) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Gly 614 (Accession # G7MUQ7-1). In the region Thr 22 - Gly 614, the AA sequence of Cynomolgus and Rhesus macaque Cadherin-6 are homologus.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Application Notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.9 kDa. The protein migrates as 80-95 kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: CDH6 (K-Cadherin (CDH6))

Alternative Name: Cadherin-6 / KCAD / CDH6

Background: Synonyms: CDH6,CAD6,KCAD,K-cadherin,Cadherin-6,
Description: Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.

Molecular Weight: 67.9 kDa

Pathways: Cell-Cell Junction Organization