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TPBG Protein (His tag)

This Recombinant TPBG protein is expressed in HEK-293 Cells.
Catalog No. ABIN7121187

Quick Overview for TPBG Protein (His tag) (ABIN7121187)

Target

See all TPBG Proteins
TPBG (Trophoblast Glycoprotein (TPBG))

Protein Type

Recombinant

Origin

  • 24
  • 3
  • 2
  • 2
Cynomolgus, Rhesus Monkey

Source

  • 21
  • 3
  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

Purity

>95 % as determined by SDS-PAGE.
  • Purification tag / Conjugate

    This TPBG protein is labelled with His tag.

    Purpose

    Cynomolgus / Rhesus macaque TPBG / 5T4 Protein, His Tag

    Sequence

    Thr 35 - Ser 355

    Characteristics

    Cynomolgus / Rhesus macaque TPBG, His Tag (TPG-C52H3) is expressed from human 293 cells (HEK293). It contains AA Thr 35 - Ser 355 (Accession # Q4R8Y9-1).

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Application Notes

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.7 kDa. The protein migrates as 55-65 kDa under reducing (R) condition due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    TPBG (Trophoblast Glycoprotein (TPBG))

    Alternative Name

    TPBG / 5T4

    Background

    Synonyms: TPBG,5T4,M6P1,5T4AG,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein,
    Description: Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.

    Molecular Weight

    36.7 kDa
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