TPBG Protein (His tag)
Quick Overview for TPBG Protein (His tag) (ABIN7121187)
Target
See all TPBG ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This TPBG protein is labelled with His tag.
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Purpose
- Cynomolgus / Rhesus macaque TPBG / 5T4 Protein, His Tag
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Sequence
- Thr 35 - Ser 355
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Characteristics
- Cynomolgus / Rhesus macaque TPBG, His Tag (TPG-C52H3) is expressed from human 293 cells (HEK293). It contains AA Thr 35 - Ser 355 (Accession # Q4R8Y9-1).
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.7 kDa. The protein migrates as 55-65 kDa under reducing (R) condition due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- TPBG (Trophoblast Glycoprotein (TPBG))
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Alternative Name
- TPBG / 5T4
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Background
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Synonyms: TPBG,5T4,M6P1,5T4AG,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein,
Description: Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development. -
Molecular Weight
- 36.7 kDa
Target
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