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NKG2A & CD94 protein (His tag)

Recombinant protein expressed in HEK-293 Cells.
Catalog No. ABIN7121284

Quick Overview for NKG2A & CD94 protein (His tag) (ABIN7121284)

Target

NKG2A & CD94

Protein Type

Recombinant

Origin

  • 8
  • 3
  • 2
  • 1
Cynomolgus

Source

  • 14
HEK-293 Cells

Purity

>95 % as determined by SDS-PAGE.
  • Purification tag / Conjugate

    His tag

    Purpose

    Cynomolgus NKG2A&CD94 Protein, His Tag

    Sequence

    Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94)

    Characteristics

    Cynomolgus NKG2A&CD94, His Tag (NC4-C52H6) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94) (Accession # Q68VD2-1 (NKG2A) & Q68VD4-1 (CD94).

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Application Notes

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30.6 kDa. The protein migrates as 35-45 kDa under reducing (R) condition due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    NKG2A & CD94

    Alternative Name

    NKG2A&CD94

    Background

    Synonyms: NKG2A & CD94,
    Description: CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

    Molecular Weight

    30.6 kDa
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