Quick Overview for Afamin Protein (AFM) (His tag) (ABIN7319846)
Target
See all Afamin (AFM) ProteinsProtein Type
Origin
Source
Purity
-
-
Purification tag / Conjugate
- This Afamin protein is labelled with His tag.
-
Purpose
- Recombinant Human Afamin/AFM (C-6His)
-
Sequence
- Leu22-Asn599
-
Characteristics
- Recombinant Human Afamin is produced by our Mammalian expression system and the target gene encoding Leu22-Asn599 is expressed with a 6His tag at the C-terminus.
-
Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Afamin (AFM) (AA 1-599) protein (GST tag)
AFM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Afamin (AFM) (AA 22-143) protein (His-IF2DI Tag)AFM Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Please refer to the printed manual for detailed information.
-
Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
-
Storage
- 4 °C,-20 °C,-80 °C
-
Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- Afamin (AFM)
-
Alternative Name
- Afamin/AFM
-
Background
-
Background: Afamin also known as Alpha -Albumin is a secreted monomeric glycoprotein of the Alb/Albumin family of molecules. AFM is known to bind and transport vitamin E family molecules, playing an important role for transporting at the blood-brain-barrier. Afamin has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. AFM also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rational for the observation that bone formation often follows bone resorption. The importance of Afamin in transport of molecules has led to a suggested diagnostic role in various diseases, including pre-eclampsia, ovarian cancer, and both gestational and type-2 diabetes.
Synonym: Afamin, AFM, ALB2, ALB2alpha-Alb, ALBA, ALBAalpha-albumin, ALF, Alpha-Alb, Alpha-albumin
-
Molecular Weight
- 67.6 kDa
-
UniProt
- P43652
Target
-
