Quick Overview for Afamin Protein (AFM) (His tag) (ABIN7319846)
Target
See all Afamin (AFM) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Afamin protein is labelled with His tag.
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Purpose
- Recombinant Human Afamin/AFM (C-6His)
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Sequence
- Leu22-Asn599
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Characteristics
- Recombinant Human Afamin is produced by our Mammalian expression system and the target gene encoding Leu22-Asn599 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Afamin (AFM) (AA 22-143) protein (His-IF2DI Tag)
AFM Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Afamin (AFM) (AA 1-599) protein (GST tag)AFM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Afamin (AFM)
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Alternative Name
- Afamin/AFM
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Background
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Background: Afamin also known as Alpha -Albumin is a secreted monomeric glycoprotein of the Alb/Albumin family of molecules. AFM is known to bind and transport vitamin E family molecules, playing an important role for transporting at the blood-brain-barrier. Afamin has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. AFM also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rational for the observation that bone formation often follows bone resorption. The importance of Afamin in transport of molecules has led to a suggested diagnostic role in various diseases, including pre-eclampsia, ovarian cancer, and both gestational and type-2 diabetes.
Synonym: Afamin, AFM, ALB2, ALB2alpha-Alb, ALBA, ALBAalpha-albumin, ALF, Alpha-Alb, Alpha-albumin
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Molecular Weight
- 67.6 kDa
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UniProt
- P43652
Target
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