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alpha 2 Antiplasmin Protein (Fc Tag)

This Recombinant alpha 2 Antiplasmin protein is produced in Human Cells.
Catalog No. ABIN7320644

Quick Overview for alpha 2 Antiplasmin Protein (Fc Tag) (ABIN7320644)

Target

See all alpha 2 Antiplasmin (SERPINF2) Proteins
alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Protein Type

Recombinant

Origin

  • 10
  • 7
  • 3
  • 2
  • 2
  • 1
Mouse

Source

  • 10
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by SDS-PAGE
  • Purification tag / Conjugate

    This alpha 2 Antiplasmin protein is labelled with Fc Tag.

    Purpose

    Recombinant Mouse SerpinF2/SERPINF2 Protein (Fc Tag)

    Sequence

    Val28-Lys491

    Characteristics

    Recombinant Mouse Serine Protease Inhibitor-clade F2 is produced by our Mammalian expression system and the target gene encoding Val28-Lys491 is expressed with a Fc tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl,20 % glycerol,1 mM DTT, pH 8.0.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

    Alternative Name

    SerpinF2/SERPINF2

    Background

    Background: Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.

    Synonym: Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, Serpin F2, Serpinf2

    Molecular Weight

    79.3 kDa

    UniProt

    Q61247

    Pathways

    Regulation of Systemic Arterial Blood Pressure by Hormones
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