ANTXR1 Protein (Fc Tag)
Quick Overview for ANTXR1 Protein (Fc Tag) (ABIN7317254)
Target
See all ANTXR1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This ANTXR1 protein is labelled with Fc Tag.
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Purpose
- Recombinant Human TEM8/ATR Protein (Fc Tag)
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Sequence
- Met 1-Ser321
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Characteristics
- A DNA sequence encoding the human ANTXR1 (Q9H6X2-4) (Met1-Ser321) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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anthrax Toxin Receptor 1 (ANTXR1) (AA 95-204) protein (His-IF2DI Tag)
ANTXR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
anthrax Toxin Receptor 1 (ANTXR1) (AA 33-321) protein (His tag)ANTXR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
anthrax Toxin Receptor 1 (ANTXR1) (AA 201-305) protein (GST tag)ANTXR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
anthrax Toxin Receptor 1 (ANTXR1) (AA 1-368) protein (GST tag)ANTXR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
anthrax Toxin Receptor 1 (ANTXR1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)ANTXR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
anthrax Toxin Receptor 1 (ANTXR1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)ANTXR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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Alternative Name
- TEM8/ATR
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Background
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Background: ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR, MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key proteins. ANTXR1 interacts with extracellular matrix proteins and with the actin cytoskeleton. It functions in cell attachment and migration. ANTXR1 also mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
Synonym: Anthrax Toxin Receptor 1, Tumor Endothelial Marker 8, ANTXR1, ATR, TEM8
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Molecular Weight
- 59.4 kDa
Target
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