BMPR1A Protein (His tag,Fc Tag)
Quick Overview for BMPR1A Protein (His tag,Fc Tag) (ABIN7318202)
Target
See all BMPR1A ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This BMPR1A protein is labelled with His tag,Fc Tag.
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Purpose
- Recombinant Human BMPRIA/ALK-3 Protein (Fc & His Tag)
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Sequence
- Gln24-Arg152
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Characteristics
- Recombinant Human Bone Morphogenetic Protein Receptor Type IA/Activin Receptor-like Kinase 3 is produced by our Mammalian expression system and the target gene encoding Gln24-Arg152 is expressed with a Fc, 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Bone Morphogenetic Protein Receptor 1A (BMPR1A) protein (His tag,Fc Tag)
BMPR1A Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 24-152) protein (Fc Tag)BMPR1A Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 24-113) protein (GST tag)BMPR1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 1-532) protein (GST tag)BMPR1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 24-152) protein (hIgG-His-tag)BMPR1A Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
Bone Morphogenetic Protein Receptor 1A (BMPR1A) (Active) protein (His tag,Fc Tag)BMPR1A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Bone Morphogenetic Protein Receptor 1A (BMPR1A) (Active) protein (His tag)BMPR1A Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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Alternative Name
- BMPRIA/ALK-3
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Background
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Background: Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).
Synonym: Bone Morphogenetic Protein Receptor Type-1A, BMP Type-1A Receptor, BMPR-1A, Activin Receptor-Like Kinase 3, ALK-3, Serine/Threonine-Protein Kinase Receptor R5, SKR5, CD292, BMPR1A, ACVRLK3, ALK3,10q23del
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Molecular Weight
- 42.1 kDa
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UniProt
- P36894
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Pathways
- Stem Cell Maintenance
Target
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