Quick Overview for CLEC10A Protein (Fc Tag) (ABIN7194472)
Target
See all CLEC10A ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CLEC10A protein is labelled with Fc Tag.
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Purpose
- Recombinant Mouse CLEC10A/CD301 Protein (Fc Tag)
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Sequence
- Gln 58-Ser 305
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Characteristics
- A DNA sequence encoding the extracellular domain of mouse CLEC10A (NP_001191181.1) (Gln 58-Ser 305) was fused with the Fc region of human IgG1 at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 1-316) protein (His tag)
custom-made CLEC10A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 1-304) protein (His tag)custom-made CLEC10A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 61-316) protein (His tag)CLEC10A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 57-304) protein (His tag)CLEC10A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 61-292) protein (His tag)CLEC10A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 1-316) protein (GST tag)CLEC10A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
C-Type Lectin Domain Family 10, Member A (CLEC10A) (AA 61-292) protein (His tag)CLEC10A Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
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Alternative Name
- CLEC10A/CD301
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Background
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Background: CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs, CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.
Synonym: CD301a,M-ASGP-BP-1,Mgl,Mgl1
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Molecular Weight
- 56.7 kDa
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NCBI Accession
- NP_001191181
Target
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