C1D Protein (GST tag)
Quick Overview for C1D Protein (GST tag) (ABIN7317380)
Target
See all C1D ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This C1D protein is labelled with GST tag.
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Purpose
- Recombinant Human C1D Protein (GST Tag)
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Sequence
- Met 1-Ser 141
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Characteristics
- A DNA sequence encoding the human C1D (Q13901) (Met 1-Ser 141) was fused with the GST tag at the N-terminus.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.5
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- C1D (C1D Nuclear Receptor Corepressor (C1D))
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Alternative Name
- C1D
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Background
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Background: C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA, this function may include MPHOSPH6. It potentiates transcriptional repression by NR1D1 and THRB. C1D nuclear receptor corepressorcan activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. It also can induce apoptosis in a p53/TP53 dependent manner.
Synonym: hC1D,LRP1,Rrp47,SUN-CoR,SUNCOR
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Molecular Weight
- 43.2 kDa
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UniProt
- Q13901
Target
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