Quick Overview for CES2 Protein (His tag) (ABIN7194592)
Target
See all CES2 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purification tag / Conjugate
- This CES2 protein is labelled with His tag.
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Purpose
- Recombinant Mouse Carboxylesterase-2/CES2 Protein (His Tag)(Active)
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Sequence
- Met 1-Lys 557
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Characteristics
- A DNA sequence encoding the extracellular domain of mouse CES2 (NP_663578.1) (Met 1-Lys 557) was expressed, with a polyhistidine tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measured by its ability to hydrolyze pnitrophenylacetate. The specific activity is >90,000 pmoles/min/μg.
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Carboxylesterase 2 (CES2) (AA 356-559) protein (His-IF2DI Tag)
CES2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Carboxylesterase 2 (CES2) (AA 1-623) protein (GST tag)CES2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Carboxylesterase 2 (CES2) (AA 514-621) protein (GST tag)CES2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Carboxylesterase 2 (CES2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CES2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Carboxylesterase 2 (CES2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CES2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CES2 (Carboxylesterase 2 (CES2))
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Alternative Name
- Carboxylesterase-2/CES2
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Background
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Background: Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.
Synonym: ces2A3
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Molecular Weight
- 60.4 kDa
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NCBI Accession
- NP_663578
Target
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