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CROT Protein (His tag)

This Recombinant CROT protein is produced in Baculovirus infected Insect Cells.
Catalog No. ABIN7317695

Quick Overview for CROT Protein (His tag) (ABIN7317695)

Target

See all CROT Proteins
CROT (Carnitine O-Octanoyltransferase (CROT))

Protein Type

Recombinant

Origin

  • 7
  • 3
  • 1
Human

Source

  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Baculovirus infected Insect Cells

Purity

> 93 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CROT protein is labelled with His tag.

    Purpose

    Recombinant Human CROT Protein (474 Leu/Val, His Tag)

    Sequence

    Met 1-Leu 612, 474 Leu/Val

    Characteristics

    A DNA sequence encoding the human CROT (Q9UKG9) (Met 1-Leu 612, 474 Leu/Val) was fused with a polyhistidine tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 10 % glycerol

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CROT (Carnitine O-Octanoyltransferase (CROT))

    Alternative Name

    CROT

    Background

    Background: Carnitine octanoyltransferase (CROT or COT), also known as octanoyl-CoA: L-carnitine O-octanoyltransferase, medium-chain/long-chain carnitine acyltransferase, and carnitine medium-chain acyltransferase, is a carnitine acyltransferase belonging to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. Carnitine octanoyltransferase (CROT or COT) facilitate the transport of medium- and long-chain fatty acids through the peroxisomal and mitochondrial membranes. It is physiologically inhibited by malonyl-CoA. COT also has functions in efficiently converting one of the end products of the peroxisomal beta-oxidation of pristanic acid, 4, 8-dimethylnonanoyl-CoA, to its corresponding carnitine ester. 

    Synonym: COT

    Molecular Weight

    71.5 kDa

    UniProt

    Q9UKG9

    Pathways

    Monocarboxylic Acid Catabolic Process
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