Cathepsin D Protein (CTSD) (His tag)
Quick Overview for Cathepsin D Protein (CTSD) (His tag) (ABIN7320739)
Target
See all Cathepsin D (CTSD) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Cathepsin D protein is labelled with His tag.
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Purpose
- Recombinant Mouse Cathepsin D/CTSD Protein (His Tag)
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Sequence
- Ile21-Leu410
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Characteristics
- Recombinant Mouse Cathepsin D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu410 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Cathepsin D (CTSD) (AA 26-412) protein (GST tag)
CTSD Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin D (CTSD) (AA 21-410) (Active) protein (His tag)CTSD Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, EAA Active
Cathepsin D (CTSD) (AA 67-403), (partial) protein (GST tag)CTSD Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM MES,150 mM NaCl, pH 5.5.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Cathepsin D (CTSD)
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Alternative Name
- Cathepsin D/CTSD
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Background
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Background: CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.
Synonym: Cathepsin D, CTSD,CPSD
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Molecular Weight
- 43.9 kDa
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NCBI Accession
- NP_034113
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Pathways
- Peptide Hormone Metabolism
Target
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