CD177 Protein (His tag)
Quick Overview for CD177 Protein (His tag) (ABIN7318970)
Target
See all CD177 ProteinsProtein Type
Origin
Source
Purity
-
-
Purification tag / Conjugate
- This CD177 protein is labelled with His tag.
-
Purpose
- Recombinant Human PRV1/CD177 Protein (His Tag)
-
Sequence
- Leu22-Gly407
-
Characteristics
- Recombinant Human Polycythemia Rubra Vera Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu22-Gly407 is expressed with a 6His tag at the C-terminus.
-
Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
CD177 Molecule (CD177) (AA 26-516) protein (His tag)
CD177 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
CD177 Molecule (CD177) (AA 22-408) protein (His-IF2DI Tag)CD177 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
CD177 Molecule (CD177) (AA 1-437) protein (GST tag)CD177 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
CD177 Molecule (CD177) proteinCD177 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
CD177 Molecule (CD177) protein (Myc-DYKDDDDK Tag)CD177 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Please refer to the printed manual for detailed information.
-
Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
-
Storage
- 4 °C,-20 °C,-80 °C
-
Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- CD177 (CD177 Molecule (CD177))
-
Alternative Name
- PRV1/CD177
-
Background
-
Background: CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.
Synonym: CD177 Antigen, Human Neutrophil Alloantigen 2a, HNA-2a, NB1 Glycoprotein, NB1 GP, Polycythemia Rubra Vera Protein 1, PRV-1, CD177, NB1, PRV1
-
Molecular Weight
- 42.3 kDa
-
UniProt
- Q8N6Q3
Target
-
