CD5L Protein (His tag)
Quick Overview for CD5L Protein (His tag) (ABIN7320432)
Target
See all CD5L ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD5L protein is labelled with His tag.
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Purpose
- Recombinant Mouse CD5L Protein (His Tag)
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Sequence
- Met 1-Val 352
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Characteristics
- A DNA sequence encoding the extracellular domain (Met 1-Val 352) of mouse CD5L (NP_033820.2) precursor was expressed with a polyhistidine tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD5L (CD5 Molecule-Like (CD5L))
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Alternative Name
- CD5L
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Background
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Background: CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.
Synonym: CD5 antigen-like,Apoptosis inhibitor expressed by macrophages,Apoptosis inhibitory 6,CT-2,SP-alpha,Cd5l,Aim, Api6,AAC-11, AI047839, Api6, CT2, Pdp, Sp-alpha
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Molecular Weight
- 38 kDa
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NCBI Accession
- NP_033820
Target
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