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CD5L Protein (His tag)

This Recombinant CD5L protein is expressed in HEK-293 Cells.
Catalog No. ABIN7320432

Quick Overview for CD5L Protein (His tag) (ABIN7320432)

Target

See all CD5L Proteins
CD5L (CD5 Molecule-Like (CD5L))

Protein Type

Recombinant

Origin

  • 8
  • 4
  • 2
Mouse

Source

  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 98 % as determined by SDS-PAGE
  • Purification tag / Conjugate

    This CD5L protein is labelled with His tag.

    Purpose

    Recombinant Mouse CD5L Protein (His Tag)

    Sequence

    Met 1-Val 352

    Characteristics

    A DNA sequence encoding the extracellular domain (Met 1-Val 352) of mouse CD5L (NP_033820.2) precursor was expressed with a polyhistidine tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg of the protein as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile PBS, pH 7.4

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD5L (CD5 Molecule-Like (CD5L))

    Alternative Name

    CD5L

    Background

    Background: CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.

    Synonym: CD5 antigen-like,Apoptosis inhibitor expressed by macrophages,Apoptosis inhibitory 6,CT-2,SP-alpha,Cd5l,Aim, Api6,AAC-11, AI047839, Api6, CT2, Pdp, Sp-alpha

    Molecular Weight

    38 kDa

    NCBI Accession

    NP_033820
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