CD7 Protein (CD7) (His tag)

Catalog No. ABIN7317687

This Recombinant CD7 protein is produced in HEK-293 Cells.

Quick Overview for CD7 Protein (CD7) (His tag) (ABIN7317687)

Target: CD7

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This CD7 protein is labelled with His tag.

Purpose: Recombinant Human CD7/GP40 Protein (His Tag)(Active)

Sequence: Met 1-Pro 180

Characteristics: A DNA sequence encoding the human CD7 (NP_006128.1) extracellular domain (Met 1-Pro 180) was expressed, with a polyhistidine tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA.Immobilized human CD7-His at 10 μg/ml (100 μl /well) can bind biotinylated SECTM1-His, The EC50 of biotinylated SECTM1-His is 11-26ng/ml.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CD7

Alternative Name: CD7/GP40

Background:

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD7 is a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell / B-cell interaction during early lymphoid development.

Synonym: T-Cell Antigen CD7, GP40, T-Cell Leukemia Antigen, T-Cell Surface Antigen Leu-9, TP41, CD7

Molecular Weight: 18 kDa

NCBI Accession: NP_006128

Pathways: Cell-Cell Junction Organization