Coagulation Factor X Protein (F10) (Fc Tag)

Catalog No. ABIN7319649

Recombinant Coagulation Factor X protein expressed in Human Cells.

Quick Overview for Coagulation Factor X Protein (F10) (Fc Tag) (ABIN7319649)

Target: Coagulation Factor X (F10)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 85 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Coagulation Factor X protein is labelled with Fc Tag.

Purpose: Recombinant Human Coagulation Factor X/F10 Protein (Fc Tag)

Sequence: Asp22-Phe96

Characteristics: Recombinant Human Coagulation Factor X is produced by our Mammalian expression system and the target gene encoding Asn32-Lys488 is expressed with a Fc tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM MES,150 mM NaCl,0.2 mM CaCl2, pH 5.5.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Coagulation Factor X (F10)

Alternative Name: Coagulation Factor X/F10

Background:

Background: F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1-40). Both the intrinsic and extrinsic pathways activate Factor X to Xa, which consists of light (residues 41-179) and heavy (residues 235-488) chains linked by a disulfide bond. Coagulation factor X is initially synthesized in the liver. The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds. Forms a heterodimer with SERPINA5. F10 is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.

Synonym: Coagulation factor 10,coagulation factor X,FX,FXA

Molecular Weight: 78.2 kDa

UniProt: P00742