C1QBP Protein (AA 74-282) (His tag)

Catalog No. ABIN7319301

This Recombinant C1QBP protein is expressed in Escherichia coli (E. coli).

Quick Overview for C1QBP Protein (AA 74-282) (His tag) (ABIN7319301)

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 85 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 74-282

Purification tag / Conjugate: This C1QBP protein is labelled with His tag.

Purpose: Recombinant Human C1QBP Protein (aa 74-282, His Tag)

Sequence: Leu74-Gln282

Characteristics: Recombinant Human Hyaluronic Acid-binding Protein is produced by our E.coli expression system and the target gene encoding Leu74-Gln282 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris, 20 % Glycerol, 1 mM DTT, pH 7.5.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Alternative Name: C1QBP

Background:

Background: Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.

Synonym: Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial, ASF/SF2-Associated Protein p32, Glycoprotein gC1qBP, C1qBP, Hyaluronan-Binding Protein 1, Mitochondrial Matrix Protein p32, gC1q-R Protein, p33, C1QBP, GC1QBP, HABP1, SF2P32,gC1qR

Molecular Weight: 24.9 kDa

NCBI Accession: NP_001203

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly