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CST3 Protein (His tag)

This Recombinant CST3 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318375

Quick Overview for CST3 Protein (His tag) (ABIN7318375)

Target

See all CST3 Proteins
CST3 (Cystatin C (CST3))

Protein Type

Recombinant

Origin

  • 16
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Human

Source

  • 17
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CST3 protein is labelled with His tag.

    Purpose

    Recombinant Human Cystatin C/CST3 Protein (E.coli, His Tag)

    Sequence

    Gly26-Ala146

    Characteristics

    Recombinant Human Cystatin C is produced by our E.coli expression system and the target gene encoding Gly26-Ala146 is expressed with a 6His tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM HEPES,150 mM NaCl, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CST3 (Cystatin C (CST3))

    Alternative Name

    Cystatin C/CST3

    Background

    Background: Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.

    Synonym: ARMD11,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin,Cystatin-3

    Molecular Weight

    16.5 kDa

    UniProt

    P01034
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