CRELD1 Protein (His tag)

Catalog No. ABIN7317246

This Recombinant CRELD1 protein is produced in HEK-293 Cells.

Quick Overview for CRELD1 Protein (His tag) (ABIN7317246)

Target: CRELD1 (Cysteine-Rich with EGF-Like Domains 1 (CRELD1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This CRELD1 protein is labelled with His tag.

Purpose: Recombinant Human CRELD1 Protein (His Tag)

Sequence: Met 1-Glu362

Characteristics: A DNA sequence encoding the human CRELD1 (NP_001070883.1) (Met1-Glu362) was expressed with a polyhistidine tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CRELD1 (Cysteine-Rich with EGF-Like Domains 1 (CRELD1))

Alternative Name: CRELD1

Background:

Background: CRELD1 is a transmembrane glycoprotein. Epidermal growth factor(EGF)­like domain exists in CRELD1. EGF-like repeats are a class of cysteine-rich domains that mediate interactions between proteins of diverse function. EGF domains are found in proteins that are either completely secreted or have transmembrane regions that tether the protein to the cell surface. CRELD1 contains a 333 amino acid acid (aa) extracellular domain (ECD), two tandem transmembrane segments, and a second ECD of 15 aa. Defects in CRELD1 may cause susceptibility to atrioventricular septal defect type 2 which results in a persistent common atrioventricular canal.

Synonym: AVSD2;CIRRIN

Molecular Weight: 37.4 kDa

NCBI Accession: NP_001070883