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DCXR Protein (His tag)

DCXR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318744
  • Target See all DCXR Proteins
    DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 4
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This DCXR protein is labelled with His tag.
    Purpose
    Recombinant Human DCXR Protein (His Tag)
    Sequence
    Met 1-Cys244
    Characteristics
    Recombinant Human L-Xylulose Reductase is produced by our E.coli expression system and the target gene encoding Met1-Cys244 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DCXR Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, 1 mM DTT, 30 % Glycerol, 1 mM DTT, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
    Alternative Name
    DCXR (DCXR Products)
    Background

    Background: L-Xylulose Reductase is an enzyme that belongs to the Short-Chain Dehydrogenases/Reductases (SDR) family. L-Xylulose Reductase is responsible for the metabolism of Xylulose, converting it into Xylitol. L-Xylulose Reductase catalyzes the NADPH-dependent reduction of several Pentoses, Tetroses, Trioses, α-Dicarbonyl compounds and L-Xylulose. L-Xylulose Reductase participates in the Uronate Cycle of Glucose metabolism. It may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing Xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.

    Synonym: L-Xylulose Reductase, XR, Carbonyl Reductase II, Dicarbonyl/L-Xylulose Reductase, Kidney Dicarbonyl Reductase, kiDCR, Sperm Surface Protein P34H, DCXR

    Molecular Weight
    28.1 kDa
    UniProt
    Q7Z4W1
    Pathways
    Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process
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