HCoV-NL63 Nucleocapsid Protein

Catalog No. ABIN7196030

Recombinant protein expressed in Escherichia coli (E. coli).

Quick Overview for HCoV-NL63 Nucleocapsid Protein (ABIN7196030)

Target: HCoV-NL63 Nucleocapsid

Protein Type: Recombinant

Origin: Human Coronavirus (HCoV)

Source: Escherichia coli (E. coli)

Purity: Greater than 85 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant HCoV-NL63 Nucleocapsid Protein

Sequence: Met1-His377 

Characteristics: Recombinant HCoV-NL63 Nucleocapsid Protein is produced by our E.coli expression system and the target gene encoding Met1-His377 is expressed with a 6His tag at the N-terminus.

Biological Activity Comment: Test in progress

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl,150 mM NaCl,50 mM Arginine, pH 7.5

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: HCoV-NL63 Nucleocapsid

Target Type: Viral Protein

Background:

Background: Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

Synonym: HCoV-NL63 Nucleocapsid Protein, HCoV-NL63 coronavirus NP Protein, HCoV-NL63 np Protein, HCoV-NL63 novel coronavirus Nucleoprotein Protein

Molecular Weight: 45.9kDa

UniProt: Q6Q1R8