HSPB8 Protein (His tag)
Quick Overview for HSPB8 Protein (His tag) (ABIN7318564)
Target
See all HSPB8 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This HSPB8 protein is labelled with His tag.
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Purpose
- Recombinant Human HSPB8 Protein (His Tag)
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Sequence
- Met 1-Thr196
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Characteristics
- Recombinant Human Heat shock protein beta-8 is produced by our E.coli expression system and the target gene encoding Met1-Thr196 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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Alternative Name
- HSPB8
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Background
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Background: Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Synonym: Heat shock protein beta-8,HspB8,Alpha-crystallin C chain,E2-induced gene 1 protein,Protein kinase H11,Small stress protein-like protein HSP22,HSPB8,CRYAC,E2IG1,HSP22
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Molecular Weight
- 22.7 kDa
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UniProt
- Q9UJY1
Target
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