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HSPB8 Protein (His tag)

This Recombinant HSPB8 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7318564

Quick Overview for HSPB8 Protein (His tag) (ABIN7318564)

Target

See all HSPB8 Proteins
HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Protein Type

Recombinant

Origin

  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
Human

Source

  • 7
  • 4
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This HSPB8 protein is labelled with His tag.

    Purpose

    Recombinant Human HSPB8 Protein (His Tag)

    Sequence

    Met 1-Thr196

    Characteristics

    Recombinant Human Heat shock protein beta-8 is produced by our E.coli expression system and the target gene encoding Met1-Thr196 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

    Alternative Name

    HSPB8

    Background

    Background: Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

    Synonym: Heat shock protein beta-8,HspB8,Alpha-crystallin C chain,E2-induced gene 1 protein,Protein kinase H11,Small stress protein-like protein HSP22,HSPB8,CRYAC,E2IG1,HSP22

    Molecular Weight

    22.7 kDa

    UniProt

    Q9UJY1
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