IGSF3 Protein (His tag)

Catalog No. ABIN7317593

This Recombinant IGSF3 protein is produced in HEK-293 Cells.

Quick Overview for IGSF3 Protein (His tag) (ABIN7317593)

Target: IGSF3 (Immunoglobulin Superfamily, Member 3 (IGSF3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 98 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This IGSF3 protein is labelled with His tag.

Purpose: Recombinant Human IGSF3/EWI-3 Protein (His Tag)

Sequence: Met 1-Ala 1124

Characteristics: A DNA sequence encoding the human IGSF3 isoform 1 (O75054-1) extracellular domain (Met 1-Ala 1124) was expressed, with a C-terminal polyhistidine tag.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: IGSF3 (Immunoglobulin Superfamily, Member 3 (IGSF3))

Alternative Name: IGSF3/EWI-3

Background:

Background: Immunoglobulin superfamily member 3 (IGSF3), also known as Glu-Trp-Ile EWI motif-containing protein 3, IgSF3 and EWI-3 and IGSF3, is a single-pass type I membrane protein which belongs to the EWI subfamily of the Ig Superfamily of molecules. IGSF3 has an overall structural similarity and strong sequence similarity to V7, a human leukocyte surface protein. IGSF3 contains eight Ig-like C2-type (immunoglobulin-like) domains. IGSF3 is expressed in a wide range of tissues with high expression in Placenta, kidney and lung. EWI-2 is part of a novel Ig subfamily that includes EWI-F (F2alpha receptor regulatory protein (FPRP), CD9P-1 ), EWI-3 (IGSF3), and EWI-101 (CD101). All four members of this Ig subfamily contain a Glu-Trp-Ile (EWI) motif not seen in other Ig proteins. Human IGSF3 shares 92 % aa identity with mouse IGSF3.

Synonym: EWI-3,LCDD,V8

Molecular Weight: 126.6 kDa