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LSM1 Protein (His tag)

This Recombinant LSM1 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7319137

Quick Overview for LSM1 Protein (His tag) (ABIN7319137)

Target

See all LSM1 Proteins
LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))

Protein Type

Recombinant

Origin

  • 6
  • 2
  • 1
  • 1
Human

Source

  • 3
  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 90 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This LSM1 protein is labelled with His tag.

    Purpose

    Recombinant Human LSM1 Protein (His Tag)

    Sequence

    Met 1-Tyr133

    Characteristics

    Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 is produced by our E.coli expression system and the target gene encoding Met1-Tyr133 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
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    Expression System HEK-293 Cells
    Conjugate His tag
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))

    Alternative Name

    LSM1

    Background

    Background: U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.

    Synonym: U6 snRNA-Associated Sm-Like Protein LSm1, Cancer-Associated Sm-Like, Small Nuclear Ribonuclear CaSm, LSM1, CASM

    Molecular Weight

    16.2 kDa

    UniProt

    O15116
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