MECR Protein (His tag)
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- Target See all MECR Proteins
- MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This MECR protein is labelled with His tag.
- Purpose
- Recombinant Human MECR Protein (His Tag)
- Sequence
- Pro54-Met373
- Characteristics
- Recombinant Human Trans-2-Enoyl-CoA Reductase Mitochondrial is produced by our Mammalian expression system and the target gene encoding Pro54-Met373 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))
- Alternative Name
- MECR (MECR Products)
- Background
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Background: Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lower levels in the placenta, liver, kidney and pancreas, with weakly or no expression in the lung. MECR exists as a homodimer, which catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. MECR may take part in the mitochondrial synthesis of fatty acids.
Synonym: Trans-2-Enoyl-CoA Reductase Mitochondrial, Nuclear Receptor-Binding Factor 1, HsNrbf-1NRBF-1, MECR, NBRF1
- Molecular Weight
- 35.7 kDa
- UniProt
- Q9BV79
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