MEGF10 Protein (His tag)

Catalog No. ABIN7317160

This Recombinant MEGF10 protein is expressed in HEK-293 Cells.

Quick Overview for MEGF10 Protein (His tag) (ABIN7317160)

Target: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This MEGF10 protein is labelled with His tag.

Purpose: Recombinant Human MEGF10 Protein (His Tag)

Sequence: Met 1-Gly857

Characteristics: A DNA sequence encoding the human MEGF10 (NP_115822.1) (Met1-Gly857) was expressed with a polyhistidine tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Alternative Name: MEGF10

Background:

Background: This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.

Synonym: EMARDD

Molecular Weight: 90.2 kDa

NCBI Accession: NP_115822

Pathways: Regulation of Muscle Cell Differentiation