OBFC1 Protein (His tag)
Quick Overview for OBFC1 Protein (His tag) (ABIN7318845)
Target
See all OBFC1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This OBFC1 protein is labelled with His tag.
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Purpose
- Recombinant Human OBFC1/STN1 Protein (His Tag)
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Sequence
- Met 1-Phe368
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Characteristics
- Recombinant Human Oligosaccharide-Binding Fold-Containing Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Phe368 is expressed with a 6His tag at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 1 mM DTT, pH 8.0.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))
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Alternative Name
- OBFC1/STN1
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Background
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Background: CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Synonym: CST Complex Subunit STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, Suppressor of Cdc Thirteen Homolog, OBFC1, STN1
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Molecular Weight
- 44.2 kDa
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UniProt
- Q9H668
Target
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