PPIA Protein
Quick Overview for PPIA Protein (ABIN7320728)
Target
See all PPIA ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Mouse Cyclophilin A Protein
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Sequence
- Met1-Leu164
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Characteristics
- Recombinant Mouse Peptidyl-prolyl Cis-trans Isomerase A is produced by our E.coli expression system and the target gene encoding Met1-Leu164 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, pH 7.4 .
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
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Alternative Name
- Cyclophilin A
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Background
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Background: Peptidyl-prolyl cis-trans isomerase A is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins(CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.
Synonym: Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A, SP18, PPIA, CYPA
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Molecular Weight
- 18 kDa
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NCBI Accession
- NP_032933
Target
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