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PPIA Protein

This Recombinant PPIA protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7320728

Quick Overview for PPIA Protein (ABIN7320728)

Target

See all PPIA Proteins
PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Protein Type

Recombinant

Origin

  • 13
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Mouse

Source

  • 22
  • 13
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by SDS-PAGE
  • Purpose

    Recombinant Mouse Cyclophilin A Protein

    Sequence

    Met1-Leu164

    Characteristics

    Recombinant Mouse Peptidyl-prolyl Cis-trans Isomerase A is produced by our E.coli expression system and the target gene encoding Met1-Leu164 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, pH 7.4 .

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

    Alternative Name

    Cyclophilin A

    Background

    Background: Peptidyl-prolyl cis-trans isomerase A is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins(CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.

    Synonym: Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A, SP18, PPIA, CYPA

    Molecular Weight

    18 kDa

    NCBI Accession

    NP_032933
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