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PPP1R1A Protein (His tag)

Recombinant PPP1R1A protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318960

Quick Overview for PPP1R1A Protein (His tag) (ABIN7318960)

Target

See all PPP1R1A Proteins
PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

Protein Type

Recombinant

Origin

  • 5
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 3
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 90 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This PPP1R1A protein is labelled with His tag.

    Purpose

    Recombinant Human PPP1R1A Protein (His Tag)

    Sequence

    Met 1-Val171

    Characteristics

    Recombinant Human Protein Phosphatase 1 Regulatory Subunit 1A is produced by our E.coli expression system and the target gene encoding Met1-Val171 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $13,686.36

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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, 50 % Glycerol, pH 8.5.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

    Alternative Name

    PPP1R1A

    Background

    Background: Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.

    Synonym: Protein Phosphatase 1 Regulatory Subunit 1A, Protein Phosphatase Inhibitor 1, I-1, IPP-1, PPP1R1A, IPP1

    Molecular Weight

    20.0 kDa

    UniProt

    Q13522

    Pathways

    Cellular Glucan Metabolic Process
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