PPP1R1A Protein (His tag)
Quick Overview for PPP1R1A Protein (His tag) (ABIN7318960)
Target
See all PPP1R1A ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
 - This PPP1R1A protein is labelled with His tag.
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Purpose
 - Recombinant Human PPP1R1A Protein (His Tag)
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Sequence
 - Met 1-Val171
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Characteristics
 - Recombinant Human Protein Phosphatase 1 Regulatory Subunit 1A is produced by our E.coli expression system and the target gene encoding Met1-Val171 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
 - < 1.0 EU per μg as determined by the LAL method.
 
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Restrictions
 - For Research Use only
 
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Format
 - Frozen, Liquid
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Buffer
 - Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, 50 % Glycerol, pH 8.5.
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Storage
 - -20 °C
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Storage Comment
 - Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
 
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- PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))
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Alternative Name
 - PPP1R1A
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Background
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Background: Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.
Synonym: Protein Phosphatase 1 Regulatory Subunit 1A, Protein Phosphatase Inhibitor 1, I-1, IPP-1, PPP1R1A, IPP1
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Molecular Weight
 - 20.0 kDa
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UniProt
 - Q13522
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Pathways
 - Cellular Glucan Metabolic Process
 
Target
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