SERPINA1 Protein (His tag)

Catalog No. ABIN7320855

Product Details

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purification tag / Conjugate: This SERPINA1 protein is labelled with His tag.

Purpose: Recombinant Mouse SerpinA1/A1AT Protein (His Tag)

Sequence: Glu25-Lys413

Characteristics: Recombinant Mouse Serpin A1 is produced by our Mammalian expression system and the target gene encoding Glu25-Lys413 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Alternative Name: SerpinA1/A1AT (SERPINA1 Products)

Background:

Background: Alpha-1-antitrypsin 1-3(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein have been found for this gene.

Synonym: Alpha-1-antitrypsin 1-3,Alpha-1 protease inhibitor 3,Alpha-1 protease inhibitor 6,Alpha-1-antitrypsin 1-6,Serine protease inhibitor 1-3,Serine protease inhibitor 1-6,Serine protease inhibitor A1c,Serpin A1c,Serpina1c,Dom3, Dom6, Spi1-3, Spi1-6

Molecular Weight: 44.5 kDa

UniProt: P07758