SORD Protein (His tag)

Catalog No. ABIN7319049

Recombinant SORD protein expressed in Human Cells.

Quick Overview for SORD Protein (His tag) (ABIN7319049)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This SORD protein is labelled with His tag.

Purpose: Recombinant Human SORD Protein (His Tag)

Sequence: Ala2-Pro357

Characteristics: Recombinant Human Sorbitol Dehydrogenase is produced by our Mammalian expression system and the target gene encoding Ala2-Pro357 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,0.2M NaCl,5 mM DTT,20 % glycerol, pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SORD

Background:

Background: Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expressed in kidney and epithelial cells of both benign and malignant prostate tissue. SORD can converts sorbitol to fructose and catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase to make up the sorbitol pathway. SORD is up-regulated by androgens and down-regulated by castration. SORD may play a role in the sperm motility by providing an energetic source for sperm.

Synonym: Sorbitol Dehydrogenase, L-Iditol 2-Dehydrogenase, SORD

Molecular Weight: 39.3 kDa

UniProt: Q00796