SPON2 Protein (His tag)

Catalog No. ABIN7319051

This Recombinant SPON2 protein is expressed in Human Cells.

Quick Overview for SPON2 Protein (His tag) (ABIN7319051)

Target: SPON2 (Spondin 2 (SPON2))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This SPON2 protein is labelled with His tag.

Purpose: Recombinant Human Spondin 2/SPON2 Protein (His Tag)

Sequence: Gln27-Val331

Characteristics: Recombinant Human Spondin2 is produced by our Mammalian expression system and the target gene encoding Gln27-Val331 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SPON2 (Spondin 2 (SPON2))

Alternative Name: Spondin 2/SPON2

Background:

Background: Spondin-2, also referred to as mindin, belongs to the F-spondin family of secreted extracellular matrix proteins. Spondins are characterised by the presence of F-spondin domains 1 and 2 (FS1 and FS2) at the N-terminus and a thrombospondin-type 1 repeat (TSR1) domain at the C-terminus. Spondin-2 functions as a pattern-recognition molecule for bacterial and viral pathogens and as an integrin ligand for inflammatory cell recruitment and T cell priming. In addition to its roles in promoting neuron outgrowth and inhibiting both cancer and angiogenesis, Spondin-2 plays an important role in the initiation of the immune response and is involved in inflammatory processes.

Synonym: Spondin-2, Differentially expressed in cancerous and non-cancerous lung cells 1, DIL-1, Mindin, SPON2

Molecular Weight: 34.4 kDa

UniProt: Q9BUD6