TNFSF15 Protein
Quick Overview for TNFSF15 Protein (ABIN7320664)
Target
See all TNFSF15 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Mouse TL1A Protein
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Sequence
- Ile76-Leu252
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Characteristics
- Recombinant Mouse TNF-like 1 is produced by our E.coli expression system and the target gene encoding Ile76-Leu252 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 91-251), (Trimer) protein (His-DYKDDDDK Tag)
TNFSF15 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 61-252) protein (His-Avi Tag,Biotin)TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 1-251) protein (His tag)custom-made TNFSF15 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 1-252) protein (His tag)custom-made TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 61-252) protein (His-Avi Tag)TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 61-252) protein (Fc Tag)TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) protein (His-DYKDDDDK-Strep II Tag)TNFSF15 Origin: Human Host: HEK-293T Cells Recombinant ELISA, SDS, WB, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) protein (His tag)TNFSF15 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 1-251) protein (GST tag)TNFSF15 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) (Active) protein (His tag)TNFSF15 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
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Alternative Name
- TL1A
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Background
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Background: Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial cells. TNFSF15 is also able to regulate the expression of several important genes involved in angiogenesis. These findings are consistent with the view that TNFSF15 functions as an autocrine cytokine to inhibit angiogenesis and stabilize the vasculature.
Synonym: Tumor Necrosis Factor Ligand Superfamily Member 15, TNF Ligand-Related Molecule 1, Vascular Endothelial Cell Growth Inhibitor, TNFSF15, TL1, VEGI
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Molecular Weight
- 20.0 kDa
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UniProt
- Q5UBV8
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Pathways
- Positive Regulation of Endopeptidase Activity, Autophagy
Target
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